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Miranda - Root Stories's avatar

Oh, Amy! I’m so happy that you’re going to be a part of this adventure with me. And THANK YOU for such a generous and beautiful write up. I can’t wait to get stuck in.

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Teri Adams's avatar

Hey Amy! I signed up!

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Miranda - Root Stories's avatar

Fantastic news, Teri! See you inside. 🙂

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Mardi Crane-Godreau, PhD's avatar

The memory course sounds wonderful.

One of my clients who had Long COVID and who may also have had some measure of geriatric dementia, has been working to re-establish his memory. Besides a Mediterranean diet, he has a routine of mild physical exercise each morning and evening. Both the diet and exercise have been shown to enhance memory. Indeed, this older gentleman continues to improve both cognitively and physically.

Perhaps these might be useful additions for others who are working on memory.

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Amy - The Tonic's avatar

Thank you for restacking, Mardi! And I’m glad your friend is seeing gains.

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Miranda - Root Stories's avatar

This sounds so interesting, Mardi. I don’t cover these aspects of memory care in the course because I’m very aware of the limits of my own knowledge and qualifications. I can share what I’ve learned and point people to outside sources of information and support but can’t advise on physical healthcare.

I’m hoping to partner with people more qualified than me on these subjects in the future. I find the intersection of all these elements of mental and physical health on memory absolutely fascinating.

It’s wonderful to hear how well your client is doing. Do you have any references related to this subject you’d be able to share? I’d love to pass these on if that was ok.

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Mardi Crane-Godreau, PhD's avatar

Hi Miranda,

I understand. I leave "advising" to providers. I'm a teacher.

I found one interesting paper that does a reasonable job laying out some of the challenges in terms of the impact of exercise on memory and other cognitive functions in older adults. Here's a quote: Physical exercise can convey a protective effect against cognitive decline in ageing and Alzheimer’s disease. While the long-term health-promoting and protective effects of exercise are encouraging, it’s potential to induce neuronal and vascular plasticity in the ageing brain is still poorly understood. It remains unclear whether exercise slows the trajectory of normal ageing by modifying vascular and metabolic risk factors and/or consistently boosts brain function by inducing structural and neurochemical changes in the hippocampus and related medial temporal lobe circuitry—brain areas that are important

for learning and memory. Hence, it remains to be established to what extent exercise interventions in old age can improve brain plasticity above and beyond preservation of function. Existing data suggest that exercise trials aiming for improvement and preservation may require different outcome measures and that the balance between the two may depend on exercise intensity and duration, the presence of preclinical Alzheimer’s disease pathology, vascular and metabolic risk factors and genetic variability. BRAIN 2016: 139; 662–673

doi:10.1093/brain/awv407

I would also recommend that you read and especially note the references in one of my posts on the topic of dementia and Long COVID. https://longcovidjourney2wellness.substack.com/p/long-covid-recovery-from-dementia

The gentleman mentioned in this post from July 2023 is the same one that I mentioned recently. Indeed, his health and cognition have continued to improve. His family is diligent with respect to daily exercise and a great diet with appropriate mitochondria supporting supplements. Get in touch is you need more help.

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Miranda - Root Stories's avatar

Thank you so much, Mardi! I’m collating resources and references to add to support materials for the course. This will be enormously helpful.

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Mardi Crane-Godreau, PhD's avatar

Not sure if you subscribe to my Substack but I frequently post materials that are potentially relevant. Happy to help.

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Amy - The Tonic's avatar

Mardi, unrelated but I responded to your magnesium comment with a question for you about what type of magnesium you suggest. Maybe you can find that comment? Thank you 🙏🏻

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Mardi Crane-Godreau, PhD's avatar

Here's the link to an article about magnesium's role in the brain.

Int. J. Mol. Sci. 2023, 24, 223. https://doi.org/10.3390/ijms24010223

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Mardi Crane-Godreau, PhD's avatar

I have not done research of types of magnesium, but in our house we take Nature Made Magnesium 250mg in the form of Magnesium Oxide. This is 60% of the recommended daily allowance. My preference would be to get it from food but it seems almost impossible to get the 400 mg that is the full recommened intake.

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Miranda - Root Stories's avatar

I do now! Thank you, Mardi.

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Molly Downhour's avatar

Several totally unrelated people have told me recently that I will or should write a book. Your post was a sign to me, so I signed up.

I find that with my Long Covid, my long term memories are intact, but my short term memory is not. I’m looking forward to further cultivating my long term memories and sustaining short term memories where possible.

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Amy - The Tonic's avatar

Great! Hopefully the course will help you zone in on possible material if you do decide to write that book. Several people lately have told me I should write a book too, but I do not have the motivation for that kind of long term project. Maybe I’ll change my mind after this course too, who knows?

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Miranda - Root Stories's avatar

Wonderful to have you on board, Molly!

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Amber Horrox's avatar

This sounds amazing !!! One of the big benefits to journalling is improved memory. This one looks to taking a deep dive into so much ! I really want to join but I feel I’ve taken enough on for now and don’t want to overload myself. I hope there will be another one in the future as this really does look great z

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Miranda - Root Stories's avatar

I’ll definitely be running the course again, Amber. I totally get the overload feeling. I’ve had to restrain myself from signing up to so many exciting things while I’ve been getting this out in the world.

I don’t have a date for the next launch yet. It depends how much tweaking I make to the content as a result of feedback in this first round. But I’ll be sure to let my Substack readers know as soon as I have a date.

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Amber Horrox's avatar

Honestly, this is incredible what you have set up. I’m so excited for you and cheerleading you on all the way here. And staying true to you whilst you did it - that is no mean fete! Can’t wait to hear how everyone gets on, I imagine it’s pretty transformative. It’s very unique too.

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Miranda - Root Stories's avatar

That you, Amber. I’m ever so slightly bowled over by the response to this. Especially as I have a very small following and almost no email list. I’m just so pleased I’ve touched on something that’s genuinely needed. It’s a much more widespread issue than I ever thought when I was battling my own way through it. I’ll certainly keep you updated. 🙂

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Mardi Crane-Godreau, PhD's avatar

Hi Amy,

We were briefly discussing magnesium recently. Since your current post is dedicated to memory, there's a quote that might be useful to some readers.

"Magnesium (Mg) is involved in the regulation of metabolism and in the maintenance of the homeostasis of all the tissues, including the brain, where it harmonizes nerve signal transmission and preserves the integrity of the blood–brain barrier." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9820677/

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KB's  FROM THE PETRI DISH's avatar

Amy - Think you are going to be interested in a link in a piece I'll be posting tomorrow night. Right up the nice piece you wrote here. In the meantime, this may be of interest to you. https://www.newyorker.com/news/annals-of-inquiry/what-would-it-mean-for-scientists-to-listen-to-patients

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